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Classical Swine Fever Virus N(pro) Antagonizes IRF3 To Prevent Interferon-Independent TLR3- and RIG-I-Mediated Apoptosis

Classical swine fever virus (CSFV) is the causative agent of classical swine fever, a notifiable disease of economic importance that causes severe leukopenia, fever, and hemorrhagic disease in domesticated pigs and wild boar across the globe. CSFV has been shown to antagonize the induction of type I...

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Detalles Bibliográficos
Autores principales: Hardy, Samuel, Jackson, Ben, Goodbourn, Stephen, Seago, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092839/
https://www.ncbi.nlm.nih.gov/pubmed/33328306
http://dx.doi.org/10.1128/JVI.01136-20