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Identification of HLA-A*02:01-Restricted Candidate Epitopes Derived from the Nonstructural Polyprotein 1a of SARS-CoV-2 That May Be Natural Targets of CD8(+) T Cell Recognition In Vivo

COVID-19 vaccines are being rapidly developed and human trials are under way. Almost all of these vaccines have been designed to induce antibodies targeting the spike protein of SARS-CoV-2 in expectation of neutralizing activities. However, nonneutralizing antibodies are at risk of causing antibody-...

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Detalles Bibliográficos
Autores principales: Takagi, Akira, Matsui, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092843/
https://www.ncbi.nlm.nih.gov/pubmed/33268522
http://dx.doi.org/10.1128/JVI.01837-20