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Spike Glycoprotein and Host Cell Determinants of SARS-CoV-2 Entry and Cytopathic Effects

SARS-CoV-2, a betacoronavirus, is the cause of the COVID-19 pandemic. The SARS-CoV-2 spike (S) glycoprotein trimer mediates virus entry into host cells and cytopathic effects (syncytium formation). We studied the contribution of several S glycoprotein features to these functions, focusing on those t...

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Detalles Bibliográficos
Autores principales:	Nguyen, Hanh T., Zhang, Shijian, Wang, Qian, Anang, Saumya, Wang, Jia, Ding, Haitao, Kappes, John C., Sodroski, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092844/ https://www.ncbi.nlm.nih.gov/pubmed/33310888 http://dx.doi.org/10.1128/JVI.02304-20

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