Cargando…

Clinical Relevance of Topical Antibiotic Use in Coselecting for Multidrug-Resistant Staphylococcus aureus: Insights from In Vitro and Ex Vivo Models

Topical antibiotic preparations, such as fusidic acid (FA) or mupirocin, are used in the prevention and treatment of superficial skin infections caused by staphylococci. Previous genomic epidemiology work has suggested an association between the widespread use of topical antibiotics and the emergenc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nong, Yi, Taiaroa, George, Pasricha, Shivani, Guérillot, Romain, Monk, Ian R., Baines, Sarah L., Carter, Glen P., Howden, Benjamin P., Williamson, Deborah A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092865/ https://www.ncbi.nlm.nih.gov/pubmed/33593834 http://dx.doi.org/10.1128/AAC.02048-20

Ejemplares similares

Rapid Emergence and Evolution of Staphylococcus aureus Clones Harboring fusC-Containing Staphylococcal Cassette Chromosome Elements
por: Baines, Sarah L., et al.
Publicado: (2016)

Remodeling of pSK1 Family Plasmids and Enhanced Chlorhexidine Tolerance in a Dominant Hospital Lineage of Methicillin-Resistant Staphylococcus aureus
por: Baines, Sarah L., et al.
Publicado: (2019)

A Clinically Selected Staphylococcus aureus clpP Mutant Survives Daptomycin Treatment by Reducing Binding of the Antibiotic and Adapting a Rod-Shaped Morphology
por: Xu, Lijuan, et al.
Publicado: (2023)

Topical Antibiotic Use Coselects for the Carriage of Mobile Genetic Elements Conferring Resistance to Unrelated Antimicrobials in Staphylococcus aureus
por: Carter, Glen P., et al.
Publicado: (2018)

Complete Reconstitution of the Vancomycin-Intermediate Staphylococcus aureus Phenotype of Strain Mu50 in Vancomycin-Susceptible S. aureus
por: Katayama, Yuki, et al.
Publicado: (2016)

The Heterodimeric ABC Transporter EfrCD Mediates Multidrug Efflux in Enterococcus faecalis
por: Hürlimann, Lea M., et al.
Publicado: (2016)

Rapid Evolution of Multidrug Resistance in a Candida lusitaniae Infection during Micafungin Monotherapy
por: Scott, Nancy E., et al.
Publicado: (2023)

Antibiotics Limit Adaptation of Drug-Resistant Staphylococcus aureus to Hypoxia
por: Hull, Rebecca C., et al.
Publicado: (2022)

Expression of Plasmodium vivax crt-o Is Related to Parasite Stage but Not Ex Vivo Chloroquine Susceptibility
por: Pava, Zuleima, et al.
Publicado: (2015)

Prevalence of Slow-Growth Vancomycin Nonsusceptibility in Methicillin-Resistant Staphylococcus aureus
por: Katayama, Yuki, et al.
Publicado: (2017)

Comprehensive Genome Analysis of Carbapenem-Resistant Strains of Raoultella Species, an Emerging Multidrug-Resistant Bacterium in Hospitals
por: Yu, Xiao, et al.
Publicado: (2019)

RexAB Promotes the Survival of Staphylococcus aureus Exposed to Multiple Classes of Antibiotics
por: Clarke, Rebecca S., et al.
Publicado: (2021)

In Vitro Tolerance of Drug-Naive Staphylococcus aureus Strain FDA209P to Vancomycin
por: Singh, Madhuri, et al.
Publicado: (2017)

Antibiotic Exposure Leads to Reduced Phage Susceptibility in Vancomycin Intermediate Staphylococcus aureus (VISA)
por: McCallin, Shawna, et al.
Publicado: (2022)

SpoT-Mediated NapA Upregulation Promotes Oxidative Stress-Induced Helicobacter pylori Biofilm Formation and Confers Multidrug Resistance
por: Zhao, Yican, et al.
Publicado: (2021)

Bifunctional Enzyme SpoT Is Involved in Biofilm Formation of Helicobacter pylori with Multidrug Resistance by Upregulating Efflux Pump Hp1174 (gluP)
por: Ge, Xiaoran, et al.
Publicado: (2018)

Emergence of Oxacillin Resistance in Stealth Methicillin-Resistant Staphylococcus aureus Due to mecA Sequence Instability
por: Goering, Richard V., et al.
Publicado: (2019)

CWHM-974 is a fluphenazine derivative with improved antifungal activity against Candida albicans due to reduced susceptibility to multidrug transporter-mediated resistance mechanisms
por: Miron-Ocampo, Aracely, et al.
Publicado: (2023)

Emergence of a Multidrug-Resistant Hypervirulent Klebsiella pneumoniae Sequence Type 23 Strain with a Rare bla(CTX-M-24)-Harboring Virulence Plasmid
por: Shen, Dingxia, et al.
Publicado: (2019)

Identification and Characterization of a Novel Major Facilitator Superfamily Efflux Pump, SA09310, Mediating Tetracycline Resistance in Staphylococcus aureus
por: Li, Daiyu, et al.
Publicado: (2023)

The Sle1 Cell Wall Amidase Is Essential for β-Lactam Resistance in Community-Acquired Methicillin-Resistant Staphylococcus aureus USA300
por: Thalsø-Madsen, Ida, et al.
Publicado: (2019)

Characterization of SCCmec Instability in Methicillin-Resistant Staphylococcus aureus Affecting Adjacent Chromosomal Regions, Including the Gene for Staphylococcal Protein A (spa)
por: Scharn, C. R., et al.
Publicado: (2022)

First Report of cfr-Carrying Plasmids in the Pandemic Sequence Type 22 Methicillin-Resistant Staphylococcus aureus Staphylococcal Cassette Chromosome mec Type IV Clone
por: Shore, Anna C., et al.
Publicado: (2016)

Copresence of tet(K) and tet(M) in Livestock-Associated Methicillin-Resistant Staphylococcus aureus Clonal Complex 398 Is Associated with Increased Fitness during Exposure to Sublethal Concentrations of Tetracycline
por: Larsen, Jesper, et al.
Publicado: (2016)

In Vitro Activity of Delafloxacin and Microbiological Response against Fluoroquinolone-Susceptible and Nonsusceptible Staphylococcus aureus Isolates from Two Phase 3 Studies of Acute Bacterial Skin and Skin Structure Infections
por: McCurdy, S., et al.
Publicado: (2017)

Repeated Emergence of Variant TetR Family Regulator, FarR, and Increased Resistance to Antimicrobial Unsaturated Fatty Acid among Clonal Complex 5 Methicillin-Resistant Staphylococcus aureus
por: Bonn, Camryn M., et al.
Publicado: (2023)

Molecular drivers of resistance to sulbactam-durlobactam in contemporary clinical isolates of Acinetobacter baumannii
por: Moussa, Samir H., et al.
Publicado: (2023)

Genomic and Metabolomic Polymorphism among Experimentally Selected Paromomycin-Resistant Leishmania donovani Strains
por: Shaw, C. D., et al.
Publicado: (2019)

In Vitro Activity of a Novel Glycopolymer against Biofilms of Burkholderia cepacia Complex Cystic Fibrosis Clinical Isolates
por: Narayanaswamy, Vidya P., et al.
Publicado: (2019)

Experimentally Engineered Mutations in a Ubiquitin Hydrolase, UBP-1, Modulate In Vivo Susceptibility to Artemisinin and Chloroquine in Plasmodium berghei
por: Simwela, Nelson V., et al.
Publicado: (2020)

The Capsule Increases Susceptibility to Last-Resort Polymyxins, but Not to Other Antibiotics, in Klebsiella pneumoniae
por: D’Angelo, Francesca, et al.
Publicado: (2023)

Exploring Cefiderocol Resistance Mechanisms in Burkholderia pseudomallei
por: Hall, Carina M., et al.
Publicado: (2023)

Structural Investigations of the Inhibition of Escherichia coli AmpC β-Lactamase by Diazabicyclooctanes
por: Lang, Pauline A., et al.
Publicado: (2021)

Microevolution of Mycobacterium tuberculosis Subpopulations and Heteroresistance in a Patient Receiving 27 Years of Tuberculosis Treatment in Germany
por: Sonnenkalb, Lindsay, et al.
Publicado: (2021)

RNA Sequencing Elucidates Drug-Specific Mechanisms of Antibiotic Tolerance and Resistance in Mycobacterium abscessus
por: Schildkraut, Jodie A., et al.
Publicado: (2022)

Antileishmanial Aminopyrazoles: Studies into Mechanisms and Stability of Experimental Drug Resistance
por: Van den Kerkhof, M., et al.
Publicado: (2020)

Azole Resistance Mechanisms in Pathogenic Malassezia furfur
por: Leong, Cheryl, et al.
Publicado: (2021)

Mutations in pmrB Confer Cross-Resistance between the LptD Inhibitor POL7080 and Colistin in Pseudomonas aeruginosa
por: Romano, Keith P., et al.
Publicado: (2019)

In Vivo Fitness Adaptations of Colistin-Resistant Acinetobacter baumannii Isolates to Oxidative Stress
por: Jones, Crystal L., et al.
Publicado: (2017)

The Evolution of Azole Resistance in Candida albicans Sterol 14α-Demethylase (CYP51) through Incremental Amino Acid Substitutions
por: Warrilow, Andrew G., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_pf09j702se8i7uebghm6ffumi8