Pleckstrin-2 is essential for erythropoiesis in β-thalassemic mice, reducing apoptosis and enhancing enucleation

Erythropoiesis involves complex interrelated molecular signals influencing cell survival, differentiation, and enucleation. Diseases associated with ineffective erythropoiesis, such as β-thalassemias, exhibit erythroid expansion and defective enucleation. Clear mechanistic determinants of what make...

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Detalles Bibliográficos
Autores principales: Feola, Maria, Zamperone, Andrea, Moskop, Daniel, Chen, Huiyong, Casu, Carla, Lama, Dechen, Di Martino, Julie, Djedaini, Mansour, Papa, Luena, Martinez, Marc Ruiz, Choesang, Tenzin, Bravo-Cordero, Jose Javier, MacKay, Matthew, Zumbo, Paul, Brinkman, Nathan, Abrams, Charles S., Rivella, Stefano, Hattangadi, Shilpa, Mason, Christopher E., Hoffman, Ronald, Ji, Peng, Follenzi, Antonia, Ginzburg, Yelena Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093212/
https://www.ncbi.nlm.nih.gov/pubmed/33941818
http://dx.doi.org/10.1038/s42003-021-02046-9

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