DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation

DNA methylation and trimethylated histone H4 Lysine 20 (H4K20me3) constitute two important heterochromatin-enriched marks that frequently cooperate in silencing repetitive elements of the mammalian genome. However, it remains elusive how these two chromatin modifications crosstalk. Here, we report t...

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Detalles Bibliográficos
Autores principales: Ren, Wendan, Fan, Huitao, Grimm, Sara A., Kim, Jae Jin, Li, Linhui, Guo, Yiran, Petell, Christopher James, Tan, Xiao-Feng, Zhang, Zhi-Min, Coan, John P., Yin, Jiekai, Kim, Dae In, Gao, Linfeng, Cai, Ling, Khudaverdyan, Nelli, Çetin, Burak, Patel, Dinshaw J., Wang, Yinsheng, Cui, Qiang, Strahl, Brian D., Gozani, Or, Miller, Kyle M., O’Leary, Seán E., Wade, Paul A., Wang, Gang Greg, Song, Jikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093215/
https://www.ncbi.nlm.nih.gov/pubmed/33941775
http://dx.doi.org/10.1038/s41467-021-22665-4

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