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A novel, complex systems approach to modelling risk of psychological distress in young adolescents

Adolescence is a period of significant anatomical and functional brain changes, and complex interactions occur between mental health risk factors. The Longitudinal Adolescent Brain Study commenced in 2018, to monitor environmental and psychosocial factors influencing mental health in 500 adolescents...

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Autores principales: Beaudequin, Denise, Schwenn, Paul, McLoughlin, Larisa T., Parker, Marcella, Boyes, Amanda, Simcock, Gabrielle, Lagopoulos, Jim, Hermens, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093239/
https://www.ncbi.nlm.nih.gov/pubmed/33941827
http://dx.doi.org/10.1038/s41598-021-88932-y
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author Beaudequin, Denise
Schwenn, Paul
McLoughlin, Larisa T.
Parker, Marcella
Boyes, Amanda
Simcock, Gabrielle
Lagopoulos, Jim
Hermens, Daniel F.
author_facet Beaudequin, Denise
Schwenn, Paul
McLoughlin, Larisa T.
Parker, Marcella
Boyes, Amanda
Simcock, Gabrielle
Lagopoulos, Jim
Hermens, Daniel F.
author_sort Beaudequin, Denise
collection PubMed
description Adolescence is a period of significant anatomical and functional brain changes, and complex interactions occur between mental health risk factors. The Longitudinal Adolescent Brain Study commenced in 2018, to monitor environmental and psychosocial factors influencing mental health in 500 adolescents, for 5 years. Participants are recruited at age 12 from the community in Australia’s Sunshine Coast region. In this baseline, cross-sectional study of N = 64 participants, we draw on the network perspective, conceptualising mental disorders as causal systems of interacting entities, to propose a Bayesian network (BN) model of lifestyle and psychosocial variables influencing chances of individuals being psychologically well or experiencing psychological distress. Sensitivity analysis of network priors revealed that psychological distress (Kessler-10) was most affected by eating behaviour. Unhealthy eating increased the chance of moderate psychological distress by 600%. Low social connectedness increased the chance of severe psychological disorder by 200%. Certainty for psychological wellness required 33% decrease in unhealthy eating behaviours, 11% decrease in low social connectedness, and 9% reduction in less physical activity. BN can augment clinician judgement in mental disorders as probabilistic decision support systems. The full potential of BN methodology in a complex systems approach to psychopathology has yet to be realised.
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spelling pubmed-80932392021-05-05 A novel, complex systems approach to modelling risk of psychological distress in young adolescents Beaudequin, Denise Schwenn, Paul McLoughlin, Larisa T. Parker, Marcella Boyes, Amanda Simcock, Gabrielle Lagopoulos, Jim Hermens, Daniel F. Sci Rep Article Adolescence is a period of significant anatomical and functional brain changes, and complex interactions occur between mental health risk factors. The Longitudinal Adolescent Brain Study commenced in 2018, to monitor environmental and psychosocial factors influencing mental health in 500 adolescents, for 5 years. Participants are recruited at age 12 from the community in Australia’s Sunshine Coast region. In this baseline, cross-sectional study of N = 64 participants, we draw on the network perspective, conceptualising mental disorders as causal systems of interacting entities, to propose a Bayesian network (BN) model of lifestyle and psychosocial variables influencing chances of individuals being psychologically well or experiencing psychological distress. Sensitivity analysis of network priors revealed that psychological distress (Kessler-10) was most affected by eating behaviour. Unhealthy eating increased the chance of moderate psychological distress by 600%. Low social connectedness increased the chance of severe psychological disorder by 200%. Certainty for psychological wellness required 33% decrease in unhealthy eating behaviours, 11% decrease in low social connectedness, and 9% reduction in less physical activity. BN can augment clinician judgement in mental disorders as probabilistic decision support systems. The full potential of BN methodology in a complex systems approach to psychopathology has yet to be realised. Nature Publishing Group UK 2021-05-03 /pmc/articles/PMC8093239/ /pubmed/33941827 http://dx.doi.org/10.1038/s41598-021-88932-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Beaudequin, Denise
Schwenn, Paul
McLoughlin, Larisa T.
Parker, Marcella
Boyes, Amanda
Simcock, Gabrielle
Lagopoulos, Jim
Hermens, Daniel F.
A novel, complex systems approach to modelling risk of psychological distress in young adolescents
title A novel, complex systems approach to modelling risk of psychological distress in young adolescents
title_full A novel, complex systems approach to modelling risk of psychological distress in young adolescents
title_fullStr A novel, complex systems approach to modelling risk of psychological distress in young adolescents
title_full_unstemmed A novel, complex systems approach to modelling risk of psychological distress in young adolescents
title_short A novel, complex systems approach to modelling risk of psychological distress in young adolescents
title_sort novel, complex systems approach to modelling risk of psychological distress in young adolescents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093239/
https://www.ncbi.nlm.nih.gov/pubmed/33941827
http://dx.doi.org/10.1038/s41598-021-88932-y
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