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Prognostic relevance of the hexosamine biosynthesis pathway activation in leiomyosarcoma

Metabolic reprogramming of tumor cells and the increase of glucose uptake is one of the hallmarks of cancer. In order to identify metabolic pathways activated in leiomyosarcoma (LMS), we analyzed transcriptomic profiles of distinct subtypes of LMS in several datasets. Primary, recurrent and metastat...

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Detalles Bibliográficos
Autores principales: Tolwani, Angela, Matusiak, Magdalena, Bui, Nam, Forgó, Erna, Varma, Sushama, Baratto, Lucia, Iagaru, Andrei, Lazar, Alexander J., van de Rijn, Matt, Przybyl, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093268/
https://www.ncbi.nlm.nih.gov/pubmed/33941787
http://dx.doi.org/10.1038/s41525-021-00193-w