Cargando…

The adaptor protein GIPC1 stabilizes the scavenger receptor SR-B1 and increases its cholesterol uptake

The scavenger receptor class B type 1 (SR-B1), a high-density lipoprotein (HDL) receptor, is a membrane glycoprotein that mediates selective uptake of HDL-cholesterol and cholesterol ester (CE) into cells. SR-B1 is subject to posttranslational regulation; however, the underlying mechanisms still rem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ziyu, Zhou, Qian, Liu, Rui, Liu, Li, Shen, Wen-Jun, Azhar, Salman, Qu, Yan-Fu, Guo, Zhigang, Hu, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093464/ https://www.ncbi.nlm.nih.gov/pubmed/33811857 http://dx.doi.org/10.1016/j.jbc.2021.100616

Ejemplares similares

Multimodal regulation of myosin VI ensemble transport by cargo adaptor protein GIPC
por: Rai, Ashim, et al.
Publicado: (2022)

Pressure and Chemical Unfolding of an α-Helical Bundle Protein: The GH2 Domain of the Protein Adaptor GIPC1
por: Dubois, Cécile, et al.
Publicado: (2021)

Therapeutic Implications of GIPC1 Silencing in Cancer
por: Chittenden, Thomas W., et al.
Publicado: (2010)

Consequences of over-expression of rat Scavenger Receptor, SR-BI, in an adrenal cell model
por: Reaven, Eve, et al.
Publicado: (2006)

Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport
por: Ramonett, Aaron, et al.
Publicado: (2022)

CAPG and GIPC1: Breast Cancer Biomarkers for Bone Metastasis Development and Treatment
por: Westbrook, Jules A., et al.
Publicado: (2016)

GIPC proteins negatively modulate Plexind1 signaling during vascular development
por: Carretero-Ortega, Jorge, et al.
Publicado: (2019)

ACTH Regulation of Adrenal SR-B1
por: Shen, Wen-Jun, et al.
Publicado: (2016)

Strength and duration of GIPC-dependent signaling networks as determinants in cancer
por: Ahmed, Tasmia, et al.
Publicado: (2020)

Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex
por: Shang, Guijun, et al.
Publicado: (2017)

CD93 and GIPC expression and localization during central nervous system inflammation
por: Liu, Chun, et al.
Publicado: (2014)

Nanoparticle Targeting and Cholesterol Flux Through Scavenger Receptor Type B-1 Inhibits Cellular Exosome Uptake
por: Plebanek, Michael P., et al.
Publicado: (2015)

SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export
por: Müller-McNicoll, Michaela, et al.
Publicado: (2016)

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells
por: Valdembri, Donatella, et al.
Publicado: (2009)

Bioinformatics analysis reveals the clinical significance of GIPC2/GPD1L for colorectal cancer using TCGA database
por: Zhao, Zhengdong, et al.
Publicado: (2022)

Functional proteomics, human genetics and cancer biology of GIPC family members
por: Katoh, Masaru
Publicado: (2013)

Native human autoantibodies targeting GIPC1 identify differential expression in malignant tumors of the breast and ovary
por: Yavelsky, Victoria, et al.
Publicado: (2008)

Silencing of Neuropilins and GIPC1 in pancreatic ductal adenocarcinoma exerts multiple cellular and molecular antitumor effects
por: Borchardt, Hannes, et al.
Publicado: (2019)

Tomato SR/CAMTA transcription factors SlSR1 and SlSR3L negatively regulate disease resistance response and SlSR1L positively modulates drought stress tolerance
por: Li, Xiaohui, et al.
Publicado: (2014)

A review of the mechanisms underlying the role of the GIPC3 gene in hereditary deafness
por: Li, Xinxin, et al.
Publicado: (2023)

GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by activating WNT signaling
por: Wang, Liang, et al.
Publicado: (2022)

Expression of Concern: Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells
Publicado: (2022)

Scavenger Receptor Class B type 1 (SR-B1) and the modifiable risk factors of stroke
por: Lenahan, Cameron, et al.
Publicado: (2019)

Inhibition of Scavenger Receptor Class B Type 1 (SR-B1) Expression and Activity as a Potential Novel Target to Disrupt Cholesterol Availability in Castration-Resistant Prostate Cancer
por: Pandey, Mitali, et al.
Publicado: (2021)

Gipc3 mutations associated with audiogenic seizures and sensorineural hearing loss in mouse and human
por: Charizopoulou, Nikoletta, et al.
Publicado: (2011)

Biophysical analysis of the plant-specific GIPC sphingolipids reveals multiple modes of membrane regulation
por: Mamode Cassim, Adiilah, et al.
Publicado: (2021)

Resveratrol intervention attenuates chylomicron secretion via repressing intestinal FXR-induced expression of scavenger receptor SR-B1
por: Pang, Juan, et al.
Publicado: (2023)

Molecular characterization and ligand binding specificity of the PDZ domain-containing protein GIPC3 from Schistosoma japonicum
por: Mu, Yi, et al.
Publicado: (2012)

The PDZ Protein GIPC Regulates Trafficking of the LPA(1) Receptor from APPL Signaling Endosomes and Attenuates the Cell’s Response to LPA
por: Varsano, Tal, et al.
Publicado: (2012)

VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells
por: Yoshida, Ayumi, et al.
Publicado: (2015)

SR-BI associates with ABCG1 and inhibits ABCG1-mediated cholesterol efflux from cells to high-density lipoprotein 3
por: Song, Guohua, et al.
Publicado: (2012)

Xestospongia muta Fraction-7 and Linoleic Acid: Effects on SR-BI Gene Expression and HDL Cholesterol Uptake
por: Azemi, Nurul Adila, et al.
Publicado: (2022)

Increased apolipoprotein M induced by lack of scavenger receptor BI is not activated via HDL-mediated cholesterol uptake in hepatocytes
por: Feng, Yue-Hua, et al.
Publicado: (2018)

GIPC-Regulated IGFBP-3 Promotes HSC Migration In Vitro and Portal Hypertension In Vivo Through a β1-Integrin Pathway
por: Yaqoob, Usman, et al.
Publicado: (2020)

Scavenger Hunt: SR-B1, Adrenal Insufficiency, IL-17A, and Neutrophilic Airway Inflammation in Asthma
por: Yao, Xianglan, et al.
Publicado: (2021)

Scavenger Receptor Class B Type 1 (SR-B1) being a Potential Biomarker for the Diagnosis of Liposarcoma and Associated with the Degree of Differentiation of Liposarcomas
por: Liu, Qianqian, et al.
Publicado: (2019)

The Drosophila GIPC Homologue Can Modulate Myosin Based Processes and Planar Cell Polarity but Is Not Essential for Development
por: Djiane, Alexandre, et al.
Publicado: (2010)

GIPC3 couples to MYO6 and PDZ domain proteins and shapes the hair cell apical region
por: Chatterjee, Paroma, et al.
Publicado: (2023)

GIPC3 couples to MYO6 and PDZ domain proteins, and shapes the hair cell apical region
por: Chatterjee, Paroma, et al.
Publicado: (2023)

Chronic Moderate Alcohol Intakes Accelerate SR-B1 Mediated Reverse Cholesterol Transport
por: Li, Menghua, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_mmeu2ldhtjepntkb3ujojbf24g