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The Role of Mcl-1 in Embryonic Neural Precursor Cell Apoptosis

Myeloid cell leukemia-1 (Mcl-1), an anti-apoptotic Bcl-2 protein, regulates neural precursor cell (NPC) survival in both the developing and adult mammalian nervous system. It is unclear when during the neurogenic period Mcl-1 becomes necessary for NPC survival and whether Bax is the sole pro-apoptot...

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Detalles Bibliográficos
Autores principales:	Flemmer, Robert T., Connolly, Sarah P., Geizer, Brittany A., Opferman, Joseph T., Vanderluit, Jacqueline L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093775/ https://www.ncbi.nlm.nih.gov/pubmed/33959612 http://dx.doi.org/10.3389/fcell.2021.659531

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