Fenofibrate (a PPAR-α Agonist) Administered During Ethanol Withdrawal Reverts Ethanol-Induced Astrogliosis and Restores the Levels of Glutamate Transporter in Ethanol-Administered Adolescent Rats

High-ethanol intake induces a neuroinflammatory response, which has been proposed as responsible for the maintenance of chronic ethanol consumption. Neuroinflammation decreases glutamate transporter (GLT-1) expression, increasing levels of glutamate that trigger dopamine release at the corticolimbic...

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Detalles Bibliográficos
Autores principales: Villavicencio-Tejo, Francisca, Flores-Bastías, Osvaldo, Marambio-Ruiz, Lucas, Pérez-Reytor, Diliana, Karahanian, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093785/
https://www.ncbi.nlm.nih.gov/pubmed/33959021
http://dx.doi.org/10.3389/fphar.2021.653175

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