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Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity
Accumulation of amyloid beta peptides is thought to initiate the pathogenesis of Alzheimer's disease. However, the precise mechanisms mediating their neurotoxicity are unclear. Our microarray analyses show that, in Drosophila models of amyloid beta 42 toxicity, genes involved in the unfolded pr...
Autores principales: | Niccoli, Teresa, Kerr, Fiona, Snoeren, Inge, Fabian, Daniel, Aleyakpo, Benjamin, Ivanov, Dobril, Sofola-Adesakin, Oyinkan, Cryar, Adam, Adcott, Jennifer, Thornton, Janet, Partridge, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093921/ https://www.ncbi.nlm.nih.gov/pubmed/33977265 http://dx.doi.org/10.1093/braincomms/fcab053 |
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