Recent advances in the understanding of the molecular pathogenesis and targeted therapy options in Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is the most common histiocytic disorder caused by the clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in the lesion. Advances in genomic sequencing techniques have improved our understanding of the pathophysiology of LCH. Activati...

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Detalles Bibliográficos
Autores principales: Suh, Jin Kyung, Kang, Sunghan, Kim, Hyery, Im, Ho Joon, Koh, Kyung-Nam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093998/
https://www.ncbi.nlm.nih.gov/pubmed/33935037
http://dx.doi.org/10.5045/br.2021.2021013

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