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Loss of interleukin-10 activates innate immunity to eradicate adult T-cell leukemia-initiating cells

Adult T-cell leukemia/lymphoma (ATL) is associated with chronic human T-cell leukemia virus type 1 infection and carries a poor pr o gnosi s. Arsenic tr ioxide (AS) and inter feron-alpha (IFN) together selectively trigger Tax viral oncoprotein degradation and cure Tax-driven murine ATL. AS/IFN/zidov...

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Detalles Bibliográficos
Autores principales: El Hajj, Hiba, Hleihel, Rita, El Sabban, Marwan, Bruneau, Julie, Zaatari, Ghazi, Cheminant, Morgane, Marçais, Ambroise, Akkouche, Abdou, Hasegawa, Hideki, Hall, William, De Thé, Hugues, Hermine, Olivier, Bazarbachi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094094/
https://www.ncbi.nlm.nih.gov/pubmed/33567810
http://dx.doi.org/10.3324/haematol.2020.264523

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