A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification

Hematopoietic development is spatiotemporally tightly regulated by defined cell-intrinsic and extrinsic modifiers. The role of cytokines has been intensively studied in adult hematopoiesis; however, their role in embryonic hematopoietic specification remains largely unexplored. Here, we used induced...

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Detalles Bibliográficos
Autores principales: Ackermann, Mania, Haake, Kathrin, Kempf, Henning, Kaschutnig, Paul, Weiss, Anna-Carina, Nguyen, Ariane H.H., Abeln, Markus, Merkert, Sylvia, Kühnel, Mark Phillip, Hartmann, Dorothee, Jonigk, Danny, Thum, Thomas, Kispert, Andreas, Milsom, Michael D., Lachmann, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094103/
https://www.ncbi.nlm.nih.gov/pubmed/32327499
http://dx.doi.org/10.3324/haematol.2019.228064

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