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SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase
During mitosis, sister chromatids attach to microtubules from opposite poles, called biorientation. Sister chromatid cohesion resists microtubule forces, generating tension, which provides the signal that biorientation has occurred. How tension silences the surveillance pathways that prevent cell cy...
Autores principales: | Su, Xue Bessie, Wang, Menglu, Schaffner, Claudia, Nerusheva, Olga O., Clift, Dean, Spanos, Christos, Kelly, David A., Tatham, Michael, Wallek, Andreas, Wu, Yehui, Rappsilber, Juri, Jeyaprakash, A. Arockia, Storchova, Zuzana, Hay, Ronald T., Marston, Adèle L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094117/ https://www.ncbi.nlm.nih.gov/pubmed/33929514 http://dx.doi.org/10.1083/jcb.202005130 |
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