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Tauroursodeoxycholic acid prevents Burkholderia pseudomallei-induced endoplasmic reticulum stress and is protective during melioidosis in mice

BACKGROUND: Burkholderia pseudomallei, a facultative intracellular bacterium, is the aetiological agent of melioidosis that is responsible for up to 40% sepsis-related mortality in epidemic areas. However, no effective vaccine is available currently, and the drug resistance is also a major problem i...

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Detalles Bibliográficos
Autores principales: Yuan, Siqi, Fang, Yao, Tang, Mengling, Hu, Zhiqiang, Rao, Chenglong, Chen, Jiangao, Xia, Yupei, Zhang, Meijuan, Yan, Jingmin, Tang, Bin, He, Xiaoyi, Xie, Jianping, Mao, Xuhu, Li, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094575/
https://www.ncbi.nlm.nih.gov/pubmed/33947331
http://dx.doi.org/10.1186/s12866-021-02199-x

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