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S1P induces proliferation of pulmonary artery smooth muscle cells by promoting YAP-induced Notch3 expression and activation

Sphingosine-1-phosphate (S1P), a natural multifunctional phospholipid, is highly increased in plasma from patients with pulmonary arterial hypertension and mediates proliferation of pulmonary artery smooth muscle cells (PASMCs) by activating the Notch3 signaling pathway. However, the mechanisms unde...

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Detalles Bibliográficos
Autores principales:	Wang, Jian, Yan, Xin, Feng, Wei, Wang, Qingting, Shi, Wenhua, Chai, Limin, Zhang, Qianqian, Chen, Yuqian, Liu, Jin, Qu, Zhan, Xie, Xinming, Li, Manxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094894/ https://www.ncbi.nlm.nih.gov/pubmed/33781742 http://dx.doi.org/10.1016/j.jbc.2021.100599

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