Cargando…
Effect of Difference in Consensus Sequence between HIV-1 Subtype A/E and Subtype B Viruses on Elicitation of Gag-Specific CD8(+) T Cells and Accumulation of HLA-Associated Escape Mutations
The Gag280 mutation is associated with HLA-C*01:02 but not with HLA-B*52:01 in subtype A/E-infected individuals, whereas this mutation is associated with HLA-B*52:01 but not with HLA-C*01:02 in subtype B infections. Although it is known that the Gag280 mutant is selected by HLA-B*52:01-restricted Ga...
Autores principales: | Zhang, Yu, Murakoshi, Hayato, Chikata, Takayuki, Akahoshi, Tomohiro, Tran, Giang Van, Nguyen, Trung Vu, Gatanaga, Hiroyuki, Nguyen, Kinh Van, Oka, Shinichi, Kuse, Nozomi, Takiguchi, Masafumi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094948/ https://www.ncbi.nlm.nih.gov/pubmed/33361435 http://dx.doi.org/10.1128/JVI.02061-20 |
Ejemplares similares
-
Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-1
por: Zhang, Yu, et al.
Publicado: (2020) -
Control of HIV-1 Replication by CD8(+) T Cells Specific for Two Novel Pol Protective Epitopes in HIV-1 Subtype A/E Infection
por: Nguyen, Hung The, et al.
Publicado: (2022) -
Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens
por: Zou, Chengcheng, et al.
Publicado: (2019) -
Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele
por: Zhang, Yu, et al.
Publicado: (2022) -
Collaboration of a Detrimental HLA-B*35:01 Allele with HLA-A*24:02 in Coevolution of HIV-1 with T Cells Leading to Poorer Clinical Outcomes
por: Kuse, Nozomi, et al.
Publicado: (2021)