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Increased Proviral DNA in Circulating Cells Correlates with Plasma Viral Rebound in Simian Immunodeficiency Virus-Infected Rhesus Macaques after Antiretroviral Therapy Interruption

The human immunodeficiency virus (HIV) reservoir is responsible for persistent viral infection, and a small number of mosaic latent cellular reservoirs promote viral rebound upon antiretroviral therapy interruption, which is the major obstacle to a cure. However, markers that determine effective the...

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Detalles Bibliográficos
Autores principales: Ziani, Widade, Shao, Jiasheng, Wang, Xiaolei, Russell-Lodrigue, Kasi, Liu, Yao-Zhong, Montaner, Luis J., Veazey, Ronald S., Xu, Huanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094949/
https://www.ncbi.nlm.nih.gov/pubmed/33408173
http://dx.doi.org/10.1128/JVI.02064-20