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Pentoxifylline improves the survival of spermatogenic cells via oxidative stress suppression and upregulation of PI3K/AKT pathway in mouse model of testicular torsion-detorsion

Testicular torsion-detorsion results in enhanced formation of free radicals which contribute to the pathophysiology of testicular tissue damage. Recent reports have identified protective role of pentoxifylline (PTX) against free radicals. Thus, we determined the protective effect of pentoxifylline a...

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Detalles Bibliográficos
Autores principales: Dhulqarnain, Akanji Omotosho, Takzaree, Nasrin, Hassanzadeh, Golamreza, Tooli, Heidar, Malekzadeh, Mehrnoush, Khanmohammadi, Nasrin, Yaghobinejad, Mahsa, Solhjoo, Somayeh, Rastegar, Tayebeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095127/
https://www.ncbi.nlm.nih.gov/pubmed/33997400
http://dx.doi.org/10.1016/j.heliyon.2021.e06868