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Pentoxifylline improves the survival of spermatogenic cells via oxidative stress suppression and upregulation of PI3K/AKT pathway in mouse model of testicular torsion-detorsion
Testicular torsion-detorsion results in enhanced formation of free radicals which contribute to the pathophysiology of testicular tissue damage. Recent reports have identified protective role of pentoxifylline (PTX) against free radicals. Thus, we determined the protective effect of pentoxifylline a...
Autores principales: | Dhulqarnain, Akanji Omotosho, Takzaree, Nasrin, Hassanzadeh, Golamreza, Tooli, Heidar, Malekzadeh, Mehrnoush, Khanmohammadi, Nasrin, Yaghobinejad, Mahsa, Solhjoo, Somayeh, Rastegar, Tayebeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095127/ https://www.ncbi.nlm.nih.gov/pubmed/33997400 http://dx.doi.org/10.1016/j.heliyon.2021.e06868 |
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