Roux-en-Y gastric bypass contributes to weight loss-independent improvement in hypothalamic inflammation and leptin sensitivity through gut-microglia-neuron-crosstalk

OBJECTIVE: Hypothalamic inflammation and endoplasmic reticulum (ER) stress are extensively linked to leptin resistance and overnutrition-related diseases. Surgical intervention remains the most efficient long-term weight-loss strategy for morbid obesity, but mechanisms underlying sustained feeding s...

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Detalles Bibliográficos
Autores principales: Chen, Jiesi, Haase, Nadine, Haange, Sven-Bastiaan, Sucher, Robert, Münzker, Julia, Jäger, Elisabeth, Schischke, Kristin, Seyfried, Florian, von Bergen, Martin, Hankir, Mohammed K., Krügel, Ute, Fenske, Wiebke K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095174/
https://www.ncbi.nlm.nih.gov/pubmed/33741533
http://dx.doi.org/10.1016/j.molmet.2021.101214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095174/
https://www.ncbi.nlm.nih.gov/pubmed/33741533
http://dx.doi.org/10.1016/j.molmet.2021.101214

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