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Phosphodiesterase 1C integrates store-operated calcium entry and cAMP signaling in leading-edge protrusions of migrating human arterial myocytes

In addition to maintaining cellular ER Ca(2+) stores, store-operated Ca(2+) entry (SOCE) regulates several Ca(2+)-sensitive cellular enzymes, including certain adenylyl cyclases (ADCYs), enzymes that synthesize the secondary messenger cyclic AMP (cAMP). Ca(2+), acting with calmodulin, can also incre...

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Detalles Bibliográficos
Autores principales:	Brzezinska, Paulina, Simpson, Nicholas J., Hubert, Fabien, Jacobs, Ariana N., Umana, M. Bibiana, MacKeil, Jodi L., Burke-Kleinman, Jonah, Payne, Darrin M., Ferguson, Alastair V., Maurice, Donald H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095186/ https://www.ncbi.nlm.nih.gov/pubmed/33789162 http://dx.doi.org/10.1016/j.jbc.2021.100606

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