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Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells
Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2. Here, we evaluate 254 COVID-19 patients longitudinally up to eight months and find durable broad-based immune responses. SARS-CoV-2 spike binding and neutralizing antibodies exhibit a bi-phasic decay with an extended half-l...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095229/ https://www.ncbi.nlm.nih.gov/pubmed/33948610 http://dx.doi.org/10.1101/2021.04.19.21255739 |
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por Cohen, Kristen W., Linderman, Susanne L., Moodie, Zoe, Czartoski, Julie, Lai, Lilin, Mantus, Grace, Norwood, Carson, Nyhoff, Lindsay E., Edara, Venkata Viswanadh, Floyd, Katharine, De Rosa, Stephen C., Ahmed, Hasan, Whaley, Rachael, Patel, Shivan N., Prigmore, Brittany, Lemos, Maria P., Davis, Carl W., Furth, Sarah, O’Keefe, James B., Gharpure, Mohini P., Gunisetty, Sivaram, Stephens, Kathy, Antia, Rustom, Zarnitsyna, Veronika I., Stephens, David S., Edupuganti, Srilatha, Rouphael, Nadine, Anderson, Evan J., Mehta, Aneesh K., Wrammert, Jens, Suthar, Mehul S., Ahmed, Rafi, McElrath, M. Juliana
Publicado 2021
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Publicado 2021
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Online
Artículo
Texto