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DNA Hypermethylation Induced by L-Methionine Leads to Oligodendroglial and Myelin Deficits and Schizophrenia-Like Behaviors in Adolescent Mice
Increasing evidence has demonstrated that in addition to dysfunction of neuronal circuitry, oligodendroglial dysfunction and/or disruption of white matter integrity are found in the brains of patients with schizophrenia. DNA methylation, a well-established risk factor for schizophrenia, has been dem...
Autores principales: | Chen, Xianjun, Huang, Nan-Xin, Cheng, Yong-Jie, Cai, Qi-Yan, Tian, Yan-Ping, Chen, Xing-Shu, Xiao, Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095669/ https://www.ncbi.nlm.nih.gov/pubmed/33958986 http://dx.doi.org/10.3389/fnins.2021.659853 |
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