Comparative analysis of bond strength and microleakage of newer generation bonding agents to enamel and dentin: An in vitro study

AIMS: This study aims to evaluate the bond strength (BS) and microleakage (ML) of the newer bonding agents to enamel and dentin. OBJECTIVE: (1) To analyze the BS between self-etch and total-etch adhesives. (2) To analyze the depth of ML between self-etch and total-etch adhesives. MATERIALS AND METHODS: Sixty mandibular premolars were fabricated and randomly divided into three groups: Group I (n = 20)-bonded with self-etch adhesive + nanohybrid, Group II (n = 20) with total-etch adhesive + micro hybrid and Group III (n = 20) with total-etch adhesive + nanocomposite. Teflon ring molds were used to make composite resin cylinders bonded to the buccal surface. Class II box cavity was prepared on the samples' proximal surface and condensed with composite resin with each group's specific bonding protocol. Shear BS and ML testing were conducted, and data analyzed. STATISTICAL ANALYSIS: Kruskal–Wallis analysis was done to statistically differentiate the BS and ML between the three experimental groups; the P < 0.05, it showed a statistically significant difference. Intergroup comparison was made using the Mann–Whitney U test. CONCLUSIONS: Within this study's limitation, resin bonded with self-etch G-Premio Bond used in selective etch technique showed the highest BS and resistance to ML.