To compare and evaluate the antimicrobial activity of three different root canal sealers: An In Vitro Study

AIM OF THE STUDY: The purpose of this study is to compare and analyze the antimicrobial activity of three different root canal sealers. MATERIALS AND METHODS: In this study, the antimicrobial activity of three different root canal sealers were compared against two strains of bacteria Enterococcus faecalis which is known to be common isolates of necrotic pulp and endodontic lesions. This test was done at various time intervals (1, 6, 15, and 60 min) using agar diffusion test and direct contact test. RESULTS: Bioceramic showed the best antimicrobial activity against E. faecalis among the three groups of sealers used. Moreover, the results were statistically analyzed. CONCLUSION: Within the limitations of this study, it can be concluded that Bioceramic sealer showed the best antimicrobial activity followed by MTA Fillapex and Apexit.