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Mechanism involved in the pathogenesis and immune response against SARS-CoV-2 infection
SARS CoV-2, a causative agent of human respiratory tract infection, was first identified in late 2019. It is a newly emerging viral disease with unsatisfactory treatments. The virus is highly contagious and has caused pandemic globally. The number of deaths is increasing exponentially, which is an a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer India
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096142/ https://www.ncbi.nlm.nih.gov/pubmed/33969150 http://dx.doi.org/10.1007/s13337-021-00687-2 |
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author | Sahu, Utkarsha Biswas, Debasis Singh, Anirudh Kumar Khare, Prashant |
author_facet | Sahu, Utkarsha Biswas, Debasis Singh, Anirudh Kumar Khare, Prashant |
author_sort | Sahu, Utkarsha |
collection | PubMed |
description | SARS CoV-2, a causative agent of human respiratory tract infection, was first identified in late 2019. It is a newly emerging viral disease with unsatisfactory treatments. The virus is highly contagious and has caused pandemic globally. The number of deaths is increasing exponentially, which is an alarming situation for mankind. The detailed mechanism of the pathogenesis and host immune responses to this virus are not fully known. Here we discuss an overview of SARS CoV-2 pathogenicity, its entry and replication mechanism, and host immune response against this deadly pathogen. Understanding these processes will help to lead the development and identification of drug targets and effective therapies. |
format | Online Article Text |
id | pubmed-8096142 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer India |
record_format | MEDLINE/PubMed |
spelling | pubmed-80961422021-05-05 Mechanism involved in the pathogenesis and immune response against SARS-CoV-2 infection Sahu, Utkarsha Biswas, Debasis Singh, Anirudh Kumar Khare, Prashant Virusdisease Review Article SARS CoV-2, a causative agent of human respiratory tract infection, was first identified in late 2019. It is a newly emerging viral disease with unsatisfactory treatments. The virus is highly contagious and has caused pandemic globally. The number of deaths is increasing exponentially, which is an alarming situation for mankind. The detailed mechanism of the pathogenesis and host immune responses to this virus are not fully known. Here we discuss an overview of SARS CoV-2 pathogenicity, its entry and replication mechanism, and host immune response against this deadly pathogen. Understanding these processes will help to lead the development and identification of drug targets and effective therapies. Springer India 2021-05-04 2021-06 /pmc/articles/PMC8096142/ /pubmed/33969150 http://dx.doi.org/10.1007/s13337-021-00687-2 Text en © Indian Virological Society 2021 |
spellingShingle | Review Article Sahu, Utkarsha Biswas, Debasis Singh, Anirudh Kumar Khare, Prashant Mechanism involved in the pathogenesis and immune response against SARS-CoV-2 infection |
title | Mechanism involved in the pathogenesis and immune response against SARS-CoV-2 infection |
title_full | Mechanism involved in the pathogenesis and immune response against SARS-CoV-2 infection |
title_fullStr | Mechanism involved in the pathogenesis and immune response against SARS-CoV-2 infection |
title_full_unstemmed | Mechanism involved in the pathogenesis and immune response against SARS-CoV-2 infection |
title_short | Mechanism involved in the pathogenesis and immune response against SARS-CoV-2 infection |
title_sort | mechanism involved in the pathogenesis and immune response against sars-cov-2 infection |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096142/ https://www.ncbi.nlm.nih.gov/pubmed/33969150 http://dx.doi.org/10.1007/s13337-021-00687-2 |
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