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The HIV-1 nucleocapsid chaperone protein forms locally compacted globules on long double-stranded DNA

The nucleocapsid (NC) protein plays key roles in Human Immunodeficiency Virus 1 (HIV-1) replication, notably by condensing and protecting the viral RNA genome and by chaperoning its reverse transcription into double-stranded DNA (dsDNA). Recent findings suggest that integration of viral dsDNA into t...

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Detalles Bibliográficos
Autores principales: Jiang, Kai, Humbert, Nicolas, K.K., Sriram, Rouzina, Ioulia, Mely, Yves, Westerlund, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096146/
https://www.ncbi.nlm.nih.gov/pubmed/33872352
http://dx.doi.org/10.1093/nar/gkab236