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SARS-CoV-2 vaccines — the biggest medical research project of the 21st century

SARS-CoV-2 has been detected in more than 141 million people and caused more than 3 million deaths worldwide. To reduce the additional loss of millions of lives until natural immunity is reached, researchers have focused on the only known method to stop the COVID-19 pandemic: vaccines. The pandemic...

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Detalles Bibliográficos
Autores principales: Kurup, Drishya, Schnell, Matthias J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096205/
https://www.ncbi.nlm.nih.gov/pubmed/34049261
http://dx.doi.org/10.1016/j.coviro.2021.04.008
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author Kurup, Drishya
Schnell, Matthias J
author_facet Kurup, Drishya
Schnell, Matthias J
author_sort Kurup, Drishya
collection PubMed
description SARS-CoV-2 has been detected in more than 141 million people and caused more than 3 million deaths worldwide. To reduce the additional loss of millions of lives until natural immunity is reached, researchers have focused on the only known method to stop the COVID-19 pandemic: vaccines. The pandemic has propelled high-speed vaccine development, some based on novel technology previously not utilized in the vaccine field. The new technology opens new possibilities and comes with challenges because the long-term performance of the new platforms is unknown. Here we review the current leading vaccine candidates against COVID-19 and outline the advantages and disadvantages as well as the unknowns of each candidate.
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spelling pubmed-80962052021-05-05 SARS-CoV-2 vaccines — the biggest medical research project of the 21st century Kurup, Drishya Schnell, Matthias J Curr Opin Virol Article SARS-CoV-2 has been detected in more than 141 million people and caused more than 3 million deaths worldwide. To reduce the additional loss of millions of lives until natural immunity is reached, researchers have focused on the only known method to stop the COVID-19 pandemic: vaccines. The pandemic has propelled high-speed vaccine development, some based on novel technology previously not utilized in the vaccine field. The new technology opens new possibilities and comes with challenges because the long-term performance of the new platforms is unknown. Here we review the current leading vaccine candidates against COVID-19 and outline the advantages and disadvantages as well as the unknowns of each candidate. Published by Elsevier B.V. 2021-08 2021-05-04 /pmc/articles/PMC8096205/ /pubmed/34049261 http://dx.doi.org/10.1016/j.coviro.2021.04.008 Text en © 2021 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kurup, Drishya
Schnell, Matthias J
SARS-CoV-2 vaccines — the biggest medical research project of the 21st century
title SARS-CoV-2 vaccines — the biggest medical research project of the 21st century
title_full SARS-CoV-2 vaccines — the biggest medical research project of the 21st century
title_fullStr SARS-CoV-2 vaccines — the biggest medical research project of the 21st century
title_full_unstemmed SARS-CoV-2 vaccines — the biggest medical research project of the 21st century
title_short SARS-CoV-2 vaccines — the biggest medical research project of the 21st century
title_sort sars-cov-2 vaccines — the biggest medical research project of the 21st century
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096205/
https://www.ncbi.nlm.nih.gov/pubmed/34049261
http://dx.doi.org/10.1016/j.coviro.2021.04.008
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