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SARS-CoV-2 vaccines — the biggest medical research project of the 21st century
SARS-CoV-2 has been detected in more than 141 million people and caused more than 3 million deaths worldwide. To reduce the additional loss of millions of lives until natural immunity is reached, researchers have focused on the only known method to stop the COVID-19 pandemic: vaccines. The pandemic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096205/ https://www.ncbi.nlm.nih.gov/pubmed/34049261 http://dx.doi.org/10.1016/j.coviro.2021.04.008 |
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author | Kurup, Drishya Schnell, Matthias J |
author_facet | Kurup, Drishya Schnell, Matthias J |
author_sort | Kurup, Drishya |
collection | PubMed |
description | SARS-CoV-2 has been detected in more than 141 million people and caused more than 3 million deaths worldwide. To reduce the additional loss of millions of lives until natural immunity is reached, researchers have focused on the only known method to stop the COVID-19 pandemic: vaccines. The pandemic has propelled high-speed vaccine development, some based on novel technology previously not utilized in the vaccine field. The new technology opens new possibilities and comes with challenges because the long-term performance of the new platforms is unknown. Here we review the current leading vaccine candidates against COVID-19 and outline the advantages and disadvantages as well as the unknowns of each candidate. |
format | Online Article Text |
id | pubmed-8096205 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-80962052021-05-05 SARS-CoV-2 vaccines — the biggest medical research project of the 21st century Kurup, Drishya Schnell, Matthias J Curr Opin Virol Article SARS-CoV-2 has been detected in more than 141 million people and caused more than 3 million deaths worldwide. To reduce the additional loss of millions of lives until natural immunity is reached, researchers have focused on the only known method to stop the COVID-19 pandemic: vaccines. The pandemic has propelled high-speed vaccine development, some based on novel technology previously not utilized in the vaccine field. The new technology opens new possibilities and comes with challenges because the long-term performance of the new platforms is unknown. Here we review the current leading vaccine candidates against COVID-19 and outline the advantages and disadvantages as well as the unknowns of each candidate. Published by Elsevier B.V. 2021-08 2021-05-04 /pmc/articles/PMC8096205/ /pubmed/34049261 http://dx.doi.org/10.1016/j.coviro.2021.04.008 Text en © 2021 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Kurup, Drishya Schnell, Matthias J SARS-CoV-2 vaccines — the biggest medical research project of the 21st century |
title | SARS-CoV-2 vaccines — the biggest medical research project of the 21st century |
title_full | SARS-CoV-2 vaccines — the biggest medical research project of the 21st century |
title_fullStr | SARS-CoV-2 vaccines — the biggest medical research project of the 21st century |
title_full_unstemmed | SARS-CoV-2 vaccines — the biggest medical research project of the 21st century |
title_short | SARS-CoV-2 vaccines — the biggest medical research project of the 21st century |
title_sort | sars-cov-2 vaccines — the biggest medical research project of the 21st century |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096205/ https://www.ncbi.nlm.nih.gov/pubmed/34049261 http://dx.doi.org/10.1016/j.coviro.2021.04.008 |
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