Cargando…
The Pif1 helicase is actively inhibited during meiotic recombination which restrains gene conversion tract length
Meiotic recombination ensures proper chromosome segregation to form viable gametes and results in gene conversions events between homologs. Conversion tracts are shorter in meiosis than in mitotically dividing cells. This results at least in part from the binding of a complex, containing the Mer3 he...
Autores principales: | Vernekar, Dipti Vinayak, Reginato, Giordano, Adam, Céline, Ranjha, Lepakshi, Dingli, Florent, Marsolier, Marie-Claude, Loew, Damarys, Guérois, Raphaël, Llorente, Bertrand, Cejka, Petr, Borde, Valérie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096244/ https://www.ncbi.nlm.nih.gov/pubmed/33823531 http://dx.doi.org/10.1093/nar/gkab232 |
Ejemplares similares
-
Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion
por: Duroc, Yann, et al.
Publicado: (2017) -
Strand annealing and motor driven activities of SMARCAL1 and ZRANB3 are stimulated by RAD51 and the paralog complex
por: Halder, Swagata, et al.
Publicado: (2022) -
The helicase Pif1 functions in the template switching pathway of DNA damage bypass
por: García-Rodríguez, Néstor, et al.
Publicado: (2018) -
The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity
por: Geronimo, Carly L, et al.
Publicado: (2018) -
Complementary roles of Pif1 helicase and single stranded DNA binding proteins in stimulating DNA replication through G-quadruplexes
por: Sparks, Melanie A, et al.
Publicado: (2019)