SIRT3 consolidates heterochromatin and counteracts senescence

Sirtuin 3 (SIRT3) is an NAD(+)-dependent deacetylase linked to a broad range of physiological and pathological processes, including aging and aging-related diseases. However, the role of SIRT3 in regulating human stem cell homeostasis remains unclear. Here we found that SIRT3 expression was downregu...

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Detalles Bibliográficos
Autores principales: Diao, Zhiqing, Ji, Qianzhao, Wu, Zeming, Zhang, Weiqi, Cai, Yusheng, Wang, Zehua, Hu, Jianli, Liu, Zunpeng, Wang, Qiaoran, Bi, Shijia, Huang, Daoyuan, Ji, Zhejun, Liu, Guang-Hui, Wang, Si, Song, Moshi, Qu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096253/
https://www.ncbi.nlm.nih.gov/pubmed/33706382
http://dx.doi.org/10.1093/nar/gkab161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096253/
https://www.ncbi.nlm.nih.gov/pubmed/33706382
http://dx.doi.org/10.1093/nar/gkab161

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