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Interferon antagonism by SARS-CoV-2: a functional study using reverse genetics

BACKGROUND: The COVID-19 agent, SARS-CoV-2, is conspecific with SARS-CoV, the causal agent of the severe acute respiratory syndrome epidemic in 2002–03. Although the viruses share a completely homologous repertoire of proteins and use the same cellular entry receptor, their transmission efficiencies...

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Detalles Bibliográficos
Autores principales: Schroeder, Simon, Pott, Fabian, Niemeyer, Daniela, Veith, Talitha, Richter, Anja, Muth, Doreen, Goffinet, Christine, Müller, Marcel A, Drosten, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096348/
https://www.ncbi.nlm.nih.gov/pubmed/33969329
http://dx.doi.org/10.1016/S2666-5247(21)00027-6