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Cancer Incidence and Mortality in the Oldest Old: A Nationwide Study in Finland
The world’s population is aging rapidly. This study reports the burden of cancer in the “oldest old” (aged ≥85 years) in Finland, 1953–2017, and estimates age-specific cancer rates in the older population (65–99 years) for 1988–2017. The Finnish Cancer Registry provided data on all cancer diagnoses,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096474/ https://www.ncbi.nlm.nih.gov/pubmed/33089310 http://dx.doi.org/10.1093/aje/kwaa236 |
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author | Tanskanen, Tomas Seppä, Karri J M Virtanen, Anni Malila, Nea K Pitkäniemi, Janne M |
author_facet | Tanskanen, Tomas Seppä, Karri J M Virtanen, Anni Malila, Nea K Pitkäniemi, Janne M |
author_sort | Tanskanen, Tomas |
collection | PubMed |
description | The world’s population is aging rapidly. This study reports the burden of cancer in the “oldest old” (aged ≥85 years) in Finland, 1953–2017, and estimates age-specific cancer rates in the older population (65–99 years) for 1988–2017. The Finnish Cancer Registry provided data on all cancer diagnoses, cancer deaths, and other deaths in cancer patients in Finland for 1953–2017. Between 1953–1957 and 2013–2017, the proportion of incident cancers in those aged ≥85 years increased from 1.5% to 9.6% (597 to 15,360 new cases), and in 2013–2017, more new cancers were diagnosed at ages ≥85 years than ages <50 years. Cancer incidence and excess mortality attributable to cancer peaked at ages 85–94 years and declined subsequently, whereas cancer-specific mortality continued to increase or plateaued. Due to demographic changes, the number of new cancers in the oldest old has increased substantially in Finland, and currently nearly 1 in 10 cancers are diagnosed in this age group. The increasing cancer burden in the oldest old poses a major challenge for health care and needs to be addressed in designing clinical research and reporting of cancer registries. In older populations with competing risks of death, we propose excess cancer mortality as a measure of cancer-related mortality. |
format | Online Article Text |
id | pubmed-8096474 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-80964742021-05-10 Cancer Incidence and Mortality in the Oldest Old: A Nationwide Study in Finland Tanskanen, Tomas Seppä, Karri J M Virtanen, Anni Malila, Nea K Pitkäniemi, Janne M Am J Epidemiol Original Contribution The world’s population is aging rapidly. This study reports the burden of cancer in the “oldest old” (aged ≥85 years) in Finland, 1953–2017, and estimates age-specific cancer rates in the older population (65–99 years) for 1988–2017. The Finnish Cancer Registry provided data on all cancer diagnoses, cancer deaths, and other deaths in cancer patients in Finland for 1953–2017. Between 1953–1957 and 2013–2017, the proportion of incident cancers in those aged ≥85 years increased from 1.5% to 9.6% (597 to 15,360 new cases), and in 2013–2017, more new cancers were diagnosed at ages ≥85 years than ages <50 years. Cancer incidence and excess mortality attributable to cancer peaked at ages 85–94 years and declined subsequently, whereas cancer-specific mortality continued to increase or plateaued. Due to demographic changes, the number of new cancers in the oldest old has increased substantially in Finland, and currently nearly 1 in 10 cancers are diagnosed in this age group. The increasing cancer burden in the oldest old poses a major challenge for health care and needs to be addressed in designing clinical research and reporting of cancer registries. In older populations with competing risks of death, we propose excess cancer mortality as a measure of cancer-related mortality. Oxford University Press 2020-10-22 /pmc/articles/PMC8096474/ /pubmed/33089310 http://dx.doi.org/10.1093/aje/kwaa236 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Original Contribution Tanskanen, Tomas Seppä, Karri J M Virtanen, Anni Malila, Nea K Pitkäniemi, Janne M Cancer Incidence and Mortality in the Oldest Old: A Nationwide Study in Finland |
title | Cancer Incidence and Mortality in the Oldest Old: A Nationwide Study in Finland |
title_full | Cancer Incidence and Mortality in the Oldest Old: A Nationwide Study in Finland |
title_fullStr | Cancer Incidence and Mortality in the Oldest Old: A Nationwide Study in Finland |
title_full_unstemmed | Cancer Incidence and Mortality in the Oldest Old: A Nationwide Study in Finland |
title_short | Cancer Incidence and Mortality in the Oldest Old: A Nationwide Study in Finland |
title_sort | cancer incidence and mortality in the oldest old: a nationwide study in finland |
topic | Original Contribution |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096474/ https://www.ncbi.nlm.nih.gov/pubmed/33089310 http://dx.doi.org/10.1093/aje/kwaa236 |
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