Therapeutic targeting with DABIL‐4 depletes myeloid suppressor cells in 4T1 triple‐negative breast cancer model

In many solid tumors including triple‐negative breast cancer (TNBC), upregulation of the interleukin‐4 receptor (IL‐4R) has been shown to promote cancer cell proliferation, apoptotic resistance, metastatic potential, and a Th2 response in the tumor microenvironment (TME). Since immunosuppressive cel...

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Detalles Bibliográficos
Autores principales: Parveen, Sadiya, Siddharth, Sumit, Cheung, Laurene S., Kumar, Alok, Shen, Jessica, Murphy, John R., Sharma, Dipali, Bishai, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096791/
https://www.ncbi.nlm.nih.gov/pubmed/33682324
http://dx.doi.org/10.1002/1878-0261.12938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096791/
https://www.ncbi.nlm.nih.gov/pubmed/33682324
http://dx.doi.org/10.1002/1878-0261.12938

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