N6-methyladenosine demethylase FTO impairs hepatic ischemia–reperfusion injury via inhibiting Drp1-mediated mitochondrial fragmentation

Despite N6-methyladenosine (m6A) is functionally important in various biological processes, its role and the underlying regulatory mechanism in the liver remain largely unexplored. In the present study, we showed that fat mass and obesity-associated protein (FTO, an m6A demethylase) was involved in...

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Detalles Bibliográficos
Autores principales: Du, Ying Dong, Guo, Wen Yuan, Han, Cong Hui, Wang, Ying, Chen, Xiao Song, Li, Da Wei, Liu, Jin Long, Zhang, Ming, Zhu, Nan, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096847/
https://www.ncbi.nlm.nih.gov/pubmed/33947842
http://dx.doi.org/10.1038/s41419-021-03622-x

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