Structure of the full-length human Pannexin1 channel and insights into its role in pyroptosis

Pannexin1 (PANX1) is a large-pore ATP efflux channel with a broad distribution, which allows the exchange of molecules and ions smaller than 1 kDa between the cytoplasm and extracellular space. In this study, we show that in human macrophages PANX1 expression is upregulated by diverse stimuli that p...

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Detalles Bibliográficos
Autores principales: Zhang, Sensen, Yuan, Baolei, Lam, Jordy Homing, Zhou, Jun, Zhou, Xuan, Ramos-Mandujano, Gerardo, Tian, Xueyuan, Liu, Yang, Han, Renmin, Li, Yu, Gao, Xin, Li, Mo, Yang, Maojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096850/
https://www.ncbi.nlm.nih.gov/pubmed/33947837
http://dx.doi.org/10.1038/s41421-021-00259-0

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