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Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis

Establishing a multidisciplinary approach regarding the treatment of spondylodiscitis and analyzing its effect compared to a single discipline approach. 361 patients diagnosed with spondylodiscitis were included in this retrospective pre-post intervention study. The treatment strategy was either est...

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Autores principales: Ntalos, D., Schoof, B., Thiesen, D. M., Viezens, L., Kleinertz, H., Rohde, H., Both, A., Luebke, A., Strahl, A., Dreimann, M., Stangenberg, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096947/
https://www.ncbi.nlm.nih.gov/pubmed/33947939
http://dx.doi.org/10.1038/s41598-021-89088-5
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author Ntalos, D.
Schoof, B.
Thiesen, D. M.
Viezens, L.
Kleinertz, H.
Rohde, H.
Both, A.
Luebke, A.
Strahl, A.
Dreimann, M.
Stangenberg, M.
author_facet Ntalos, D.
Schoof, B.
Thiesen, D. M.
Viezens, L.
Kleinertz, H.
Rohde, H.
Both, A.
Luebke, A.
Strahl, A.
Dreimann, M.
Stangenberg, M.
author_sort Ntalos, D.
collection PubMed
description Establishing a multidisciplinary approach regarding the treatment of spondylodiscitis and analyzing its effect compared to a single discipline approach. 361 patients diagnosed with spondylodiscitis were included in this retrospective pre-post intervention study. The treatment strategy was either established by a single discipline approach (n = 149, year 2003–2011) or by a weekly multidisciplinary infections conference (n = 212, year 2013–2018) consisting of at least an orthopedic surgeon, medical microbiologist, infectious disease specialist and pathologist. Recorded data included the surgical and antibiotic strategy, complications leading to operative revision, recovered microorganisms, as well as the total length of hospital and intensive care unit stay. Compared to a single discipline approach, performing the multidisciplinary infections conference led to significant changes in anti-infective and surgical treatment strategies. Patients discussed in the conference showed significantly reduced days of total antibiotic treatment (66 ± 31 vs 104 ± 31, p < 0.001). Moreover, one stage procedures and open transpedicular screw placement were more frequently performed following multidisciplinary discussions, while there were less involved spinal segments in terms of internal fixation as well as an increased use of intervertebral cages instead of autologous bone graft (p < 0.001). Staphylococcus aureus and Staphylococcus epidermidis were the most frequently recovered organisms in both patient groups. No significant difference was found comparing inpatient complications between the two groups or the total in-hospital stay. Implementation of a weekly infections conference is an effective approach to introduce multidisciplinarity into spondylodiscitis management. These conferences significantly altered the treatment plan compared to a single discipline approach. Therefore, we highly recommend the implementation to optimize treatment modalities for patients.
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spelling pubmed-80969472021-05-05 Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis Ntalos, D. Schoof, B. Thiesen, D. M. Viezens, L. Kleinertz, H. Rohde, H. Both, A. Luebke, A. Strahl, A. Dreimann, M. Stangenberg, M. Sci Rep Article Establishing a multidisciplinary approach regarding the treatment of spondylodiscitis and analyzing its effect compared to a single discipline approach. 361 patients diagnosed with spondylodiscitis were included in this retrospective pre-post intervention study. The treatment strategy was either established by a single discipline approach (n = 149, year 2003–2011) or by a weekly multidisciplinary infections conference (n = 212, year 2013–2018) consisting of at least an orthopedic surgeon, medical microbiologist, infectious disease specialist and pathologist. Recorded data included the surgical and antibiotic strategy, complications leading to operative revision, recovered microorganisms, as well as the total length of hospital and intensive care unit stay. Compared to a single discipline approach, performing the multidisciplinary infections conference led to significant changes in anti-infective and surgical treatment strategies. Patients discussed in the conference showed significantly reduced days of total antibiotic treatment (66 ± 31 vs 104 ± 31, p < 0.001). Moreover, one stage procedures and open transpedicular screw placement were more frequently performed following multidisciplinary discussions, while there were less involved spinal segments in terms of internal fixation as well as an increased use of intervertebral cages instead of autologous bone graft (p < 0.001). Staphylococcus aureus and Staphylococcus epidermidis were the most frequently recovered organisms in both patient groups. No significant difference was found comparing inpatient complications between the two groups or the total in-hospital stay. Implementation of a weekly infections conference is an effective approach to introduce multidisciplinarity into spondylodiscitis management. These conferences significantly altered the treatment plan compared to a single discipline approach. Therefore, we highly recommend the implementation to optimize treatment modalities for patients. Nature Publishing Group UK 2021-05-04 /pmc/articles/PMC8096947/ /pubmed/33947939 http://dx.doi.org/10.1038/s41598-021-89088-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ntalos, D.
Schoof, B.
Thiesen, D. M.
Viezens, L.
Kleinertz, H.
Rohde, H.
Both, A.
Luebke, A.
Strahl, A.
Dreimann, M.
Stangenberg, M.
Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis
title Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis
title_full Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis
title_fullStr Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis
title_full_unstemmed Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis
title_short Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis
title_sort implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096947/
https://www.ncbi.nlm.nih.gov/pubmed/33947939
http://dx.doi.org/10.1038/s41598-021-89088-5
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