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YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathways
Endometrial stromal sarcoma (ESS) is the second most common subtype of uterine mesenchymal cancer, after leiomyosarcoma, and oncogenic fusion proteins are found in many ESS. Our previous studies demonstrated transforming properties and diagnostic relevance of the fusion oncoprotein YWHAE–NUTM2 in hi...
Autores principales: | Ou, Wen-Bin, Lundberg, Meijun Z., Zhu, Shuihao, Bahri, Nacef, Kyriazoglou, Anastasios, Xu, Liangliang, Chen, Ting, Mariño-Enriquez, Adrian, Fletcher, Jonathan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097009/ https://www.ncbi.nlm.nih.gov/pubmed/33947829 http://dx.doi.org/10.1038/s41389-021-00327-w |
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