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Periplocin and cardiac glycosides suppress the unfolded protein response
The unfolded protein response (UPR) controls protein homeostasis through transcriptional and translational regulation. However, dysregulated UPR signaling has been associated with the pathogenesis of many human diseases. Therefore, the compounds modulating UPR may provide molecular insights for thes...
Autores principales: | Tokugawa, Muneshige, Inoue, Yasumichi, Ishiuchi, Kan’ichiro, Kujirai, Chisane, Matsuno, Michiyo, Ri, Masaki, Itoh, Yuka, Miyajima, Chiharu, Morishita, Daisuke, Ohoka, Nobumichi, Iida, Shinsuke, Mizukami, Hajime, Makino, Toshiaki, Hayashi, Hidetoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097017/ https://www.ncbi.nlm.nih.gov/pubmed/33947921 http://dx.doi.org/10.1038/s41598-021-89074-x |
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