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Periplocin and cardiac glycosides suppress the unfolded protein response

The unfolded protein response (UPR) controls protein homeostasis through transcriptional and translational regulation. However, dysregulated UPR signaling has been associated with the pathogenesis of many human diseases. Therefore, the compounds modulating UPR may provide molecular insights for thes...

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Detalles Bibliográficos
Autores principales: Tokugawa, Muneshige, Inoue, Yasumichi, Ishiuchi, Kan’ichiro, Kujirai, Chisane, Matsuno, Michiyo, Ri, Masaki, Itoh, Yuka, Miyajima, Chiharu, Morishita, Daisuke, Ohoka, Nobumichi, Iida, Shinsuke, Mizukami, Hajime, Makino, Toshiaki, Hayashi, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097017/
https://www.ncbi.nlm.nih.gov/pubmed/33947921
http://dx.doi.org/10.1038/s41598-021-89074-x

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