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Sumoylation of the Carboxy-Terminal of Human Cytomegalovirus DNA Polymerase Processivity Factor UL44 Attenuates Viral DNA Replication

Controlled regulation of genomic DNA synthesis is a universally conserved process for all herpesviruses, including human cytomegalovirus (HCMV), and plays a key role in viral pathogenesis, such as persistent infections. HCMV DNA polymerase processivity factor UL44 plays an essential role in viral DN...

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Detalles Bibliográficos
Autores principales: Chen, Jun, Li, Guanlie, He, Haiqing, Li, Xin, Niu, Wenjing, Cao, Di, Shen, Ao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097051/
https://www.ncbi.nlm.nih.gov/pubmed/33967989
http://dx.doi.org/10.3389/fmicb.2021.652719