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Targeting RFWD2 as an Effective Strategy to Inhibit Cellular Proliferation and Overcome Drug Resistance to Proteasome Inhibitor in Multiple Myeloma

The potential to overcome resistance to proteasome inhibitors is greatly related with ubiquitin-proteasome system during multiple myeloma (MM) treatment process. The constitutive photomorphogenic 1 (RFWD2), referred to an E3 ubiquitin ligase, has been identified as an oncogene in multiple cancers, y...

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Detalles Bibliográficos
Autores principales:	Guo, Mengjie, Ding, Pinggang, Zhu, Zhen, Fan, Lu, Zhou, Yanyan, Yang, Shu, Yang, Ye, Gu, Chunyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097052/ https://www.ncbi.nlm.nih.gov/pubmed/33968945 http://dx.doi.org/10.3389/fcell.2021.675939

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