Cargando…
Single-keratinocyte transcriptomic analyses identify different clonal types and proliferative potential mediated by FOXM1 in human epidermal stem cells
Autologous epidermal cultures restore a functional epidermis on burned patients. Transgenic epidermal grafts do so also in genetic skin diseases such as Junctional Epidermolysis Bullosa. Clinical success strictly requires an adequate number of epidermal stem cells, detected as holoclone-forming cell...
Autores principales: | Enzo, Elena, Secone Seconetti, Alessia, Forcato, Mattia, Tenedini, Elena, Polito, Maria Pia, Sala, Irene, Carulli, Sonia, Contin, Roberta, Peano, Clelia, Tagliafico, Enrico, Bicciato, Silvio, Bondanza, Sergio, De Luca, Michele |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097075/ https://www.ncbi.nlm.nih.gov/pubmed/33947848 http://dx.doi.org/10.1038/s41467-021-22779-9 |
Ejemplares similares
-
Dynamic Transcriptional and Epigenetic Regulation of Human Epidermal Keratinocyte Differentiation
por: Cavazza, Alessia, et al.
Publicado: (2016) -
Downregulation of 14-3-3σ Prevents Clonal Evolution and Leads to Immortalization of Primary Human Keratinocytes
por: Dellambra, Elena, et al.
Publicado: (2000) -
Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes
por: Teh, Muy-Teck, et al.
Publicado: (2010) -
Integrated analysis of microRNA and mRNA expression profiles in physiological myelopoiesis: role of hsa-mir-299-5p in CD34+ progenitor cells commitment
por: Tenedini, E, et al.
Publicado: (2010) -
Computational methods for the integrative analysis of single-cell data
por: Forcato, Mattia, et al.
Publicado: (2020)