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Bidirectional Genetic Control of Phenotypic Heterogeneity and Its Implication for Cancer Drug Resistance

Negative genetic regulators of phenotypic heterogeneity, or phenotypic capacitors/stabilizers, elevate population average fitness by limiting deviation from the optimal phenotype and increase the efficacy of natural selection by enhancing the phenotypic differences among genotypes. Stabilizers can p...

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Detalles Bibliográficos
Autores principales:	Mo, Ning, Zhang, Xiaoyu, Shi, Wenjun, Yu, Gongwang, Chen, Xiaoshu, Yang, Jian-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Discoveries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097262/ https://www.ncbi.nlm.nih.gov/pubmed/33355660 http://dx.doi.org/10.1093/molbev/msaa332

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