Cargando…

NeutrobodyPlex—monitoring SARS‐CoV‐2 neutralizing immune responses using nanobodies

In light of the COVID‐19 pandemic, there is an ongoing need for diagnostic tools to monitor the immune status of large patient cohorts and the effectiveness of vaccination campaigns. Here, we present 11 unique nanobodies (Nbs) specific for the SARS‐CoV‐2 spike receptor‐binding domain (RBD), of which...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wagner, Teresa R, Ostertag, Elena, Kaiser, Philipp D, Gramlich, Marius, Ruetalo, Natalia, Junker, Daniel, Haering, Julia, Traenkle, Bjoern, Becker, Matthias, Dulovic, Alex, Schweizer, Helen, Nueske, Stefan, Scholz, Armin, Zeck, Anne, Schenke‐Layland, Katja, Nelde, Annika, Strengert, Monika, Walz, Juliane S, Zocher, Georg, Stehle, Thilo, Schindler, Michael, Schneiderhan‐Marra, Nicole, Rothbauer, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097376/ https://www.ncbi.nlm.nih.gov/pubmed/33904225 http://dx.doi.org/10.15252/embr.202052325

Ejemplares similares

Immune response to SARS-CoV-2 variants of concern in vaccinated individuals
por: Becker, Matthias, et al.
Publicado: (2021)

Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity
por: Becker, Matthias, et al.
Publicado: (2021)

COVID-19 patient serum less potently inhibits ACE2-RBD binding for various SARS-CoV-2 RBD mutants
por: Junker, Daniel, et al.
Publicado: (2022)

Biparatopic nanobodies protect mice from lethal challenge with SARS‐CoV‐2 variants of concern
por: Wagner, Teresa R, et al.
Publicado: (2021)

Antibody Binding and Angiotensin-Converting Enzyme 2 Binding Inhibition Is Significantly Reduced for Both the BA.1 and BA.2 Omicron Variants
por: Junker, Daniel, et al.
Publicado: (2022)

Single-Domain Antibodies for Targeting, Detection, and In Vivo Imaging of Human CD4(+) Cells
por: Traenkle, Bjoern, et al.
Publicado: (2021)

Diminishing Immune Responses against Variants of Concern in Dialysis Patients 4 Months after SARS-CoV-2 mRNA Vaccination
por: Dulovic, Alex, et al.
Publicado: (2022)

Longitudinal cellular and humoral immune responses after triple BNT162b2 and fourth full-dose mRNA-1273 vaccination in haemodialysis patients
por: Becker, Matthias, et al.
Publicado: (2022)

A Nanobody-Based Toolset to Monitor and Modify the Mitochondrial GTPase Miro1
por: Fagbadebo, Funmilayo O., et al.
Publicado: (2022)

Peptides in headlock – a novel high-affinity and versatile peptide-binding nanobody for proteomics and microscopy
por: Braun, Michael B., et al.
Publicado: (2016)

Cellular and humoral immunogenicity of a SARS-CoV-2 mRNA vaccine in patients on haemodialysis
por: Strengert, Monika, et al.
Publicado: (2021)

HDX-MS for Epitope Characterization of a Therapeutic ANTIBODY Candidate on the Calcium-Binding Protein Annexin-A1
por: Gramlich, Marius, et al.
Publicado: (2021)

To PLEX or Not to PLEX for Amiodarone-Induced Thyrotoxicosis
por: Ahuja, Tania, et al.
Publicado: (2023)

Under the Microscope: Single-Domain Antibodies for Live-Cell Imaging and Super-Resolution Microscopy
por: Traenkle, Bjoern, et al.
Publicado: (2017)

Real-time analysis of epithelial-mesenchymal transition using fluorescent single-domain antibodies
por: Maier, Julia, et al.
Publicado: (2015)

Comparative Magnitude and Persistence of Humoral SARS-CoV-2 Vaccination Responses in the Adult Population in Germany
por: Dulovic, Alex, et al.
Publicado: (2022)

Borrelia multiplex: a bead-based multiplex assay for the simultaneous detection of Borrelia specific IgG/IgM class antibodies
por: Häring, Julia, et al.
Publicado: (2022)

Raman Microspectroscopy Identifies Biochemical Activation Fingerprints in THP-1- and PBMC-Derived Macrophages
por: Feuerer, Nora, et al.
Publicado: (2022)

Comparison of 4-plex to 8-plex iTRAQ Quantitative Measurements of Proteins in Human Plasma Samples
por: Pottiez, Gwenael, et al.
Publicado: (2012)

BioPlexR and BioPlexPy: integrated data products for the analysis of human protein interactions
por: Geistlinger, Ludwig, et al.
Publicado: (2023)

A peptide tag-specific nanobody enables high-quality labeling for dSTORM imaging
por: Virant, David, et al.
Publicado: (2018)

Raman spectroscopy in biomedicine – non-invasive in vitro analysis of cells and extracellular matrix components in tissues
por: Brauchle, Eva, et al.
Publicado: (2013)

Powering up the mu-PLEX chip
por: Tuuva, T, et al.
Publicado: (1986)

Multiplex Assay for Simultaneous Detection of Mycoplasma genitalium and Macrolide Resistance Using PlexZyme and PlexPrime Technology
por: Tabrizi, Sepehr N., et al.
Publicado: (2016)

Peptide Labeling with Isobaric Tags Yields Higher Identification Rates Using iTRAQ 4-Plex Compared to TMT 6-Plex and iTRAQ 8-Plex on LTQ Orbitrap
por: Pichler, Peter, et al.
Publicado: (2010)

A novel epitope tagging system to visualize and monitor antigens in live cells with chromobodies
por: Traenkle, Bjoern, et al.
Publicado: (2020)

Structure of the HCMV UL16-MICB Complex Elucidates Select Binding of a Viral Immunoevasin to Diverse NKG2D Ligands
por: Müller, Steffen, et al.
Publicado: (2010)

Prospects for regenerative medicine approaches in women's health
por: Schenke‐Layland, Katja, et al.
Publicado: (2015)

Neoantigens in Hematological Malignancies—Ultimate Targets for Immunotherapy?
por: Roerden, Malte, et al.
Publicado: (2019)

Unmixing for ultra-high-plex fluorescence imaging
por: Enninful, Archibald, et al.
Publicado: (2022)

A Strategy to Optimize the Generation of Stable Chromobody Cell Lines for Visualization and Quantification of Endogenous Proteins in Living Cells
por: Keller, Bettina-Maria, et al.
Publicado: (2019)

Lipidome profiling with Raman microspectroscopy identifies macrophage response to surface topographies of implant materials
por: Feuerer, Nora, et al.
Publicado: (2021)

Controlled Heterotypic Pseudo-Islet Assembly of Human β-Cells and Human Umbilical Vein Endothelial Cells Using Magnetic Levitation
por: Urbanczyk, Max, et al.
Publicado: (2020)

Generation and Assessment of Functional Biomaterial Scaffolds for Applications in Cardiovascular Tissue Engineering and Regenerative Medicine
por: Hinderer, Svenja, et al.
Publicado: (2015)

The Peptide Vaccine of the Future
por: Nelde, Annika, et al.
Publicado: (2021)

Improved targeting of human CD4(+) T cells by nanobody-modified AAV2 gene therapy vectors
por: Hamann, Martin V., et al.
Publicado: (2021)

Special Issue: Nanobody
por: Chames, Patrick, et al.
Publicado: (2020)

Antigen Targets for the Development of Immunotherapies in Leukemia
por: Bauer, Jens, et al.
Publicado: (2019)

A Collagen-based Scaffold Delivering Exogenous MicroRNA-29B to Modulate Extracellular Matrix Remodeling
por: Monaghan, Michael, et al.
Publicado: (2014)

Humoral immune response to SARS-CoV-2 and endemic coronaviruses in urban and indigenous children in Colombia
por: Fernández Villalobos, Nathalie Verónica, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gm77horiiblqfr5h359ob6sf8r