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MYBL2 and ATM suppress replication stress in pluripotent stem cells

Replication stress, a major cause of genome instability in cycling cells, is mainly prevented by the ATR‐dependent replication stress response pathway in somatic cells. However, the replication stress response pathway in embryonic stem cells (ESCs) may be different due to alterations in cell cycle p...

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Detalles Bibliográficos
Autores principales: Blakemore, Daniel, Vilaplana‐Lopera, Nuria, Almaghrabi, Ruba, Gonzalez, Elena, Moya, Miriam, Ward, Carl, Murphy, George, Gambus, Agnieszka, Petermann, Eva, Stewart, Grant S, García, Paloma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097389/
https://www.ncbi.nlm.nih.gov/pubmed/33779025
http://dx.doi.org/10.15252/embr.202051120