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Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome

X chromosome inactivation (XCI) is a dosage compensation mechanism in female mammals whereby transcription from one X chromosome is repressed. Analysis of human induced pluripotent stem cells (iPSCs) derived from female donors identified that low levels of XIST RNA correlated strongly with erosion o...

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Detalles Bibliográficos
Autores principales:	Brenes, Alejandro J., Yoshikawa, Harunori, Bensaddek, Dalila, Mirauta, Bogdan, Seaton, Daniel, Hukelmann, Jens L., Jiang, Hao, Stegle, Oliver, Lamond, Angus I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097692/ https://www.ncbi.nlm.nih.gov/pubmed/33910018 http://dx.doi.org/10.1016/j.celrep.2021.109032

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