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Alterations of Cytochrome P450s and UDP-Glucuronosyltransferases in Brain Under Diseases and Their Clinical Significances

Cytochrome P450s (CYPs) and UDP-glucuronosyltransferases (UGTs) are both greatly important metabolic enzymes in various tissues, including brain. Although expressions of brain CYPs and UGTs and their contributions to drug disposition are much less than liver, both CYPs and UGTs also mediate metaboli...

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Detalles Bibliográficos
Autores principales: Sheng, Yun, Yang, Hanyu, Wu, Tong, Zhu, Liang, Liu, Li, Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097730/
https://www.ncbi.nlm.nih.gov/pubmed/33967789
http://dx.doi.org/10.3389/fphar.2021.650027