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The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells

The only currently available approach to early efficacy testing of tuberculosis (TB) vaccine candidates is in vivo preclinical challenge models. These typically include mice, guinea pigs and non-human primates (NHPs), which must be exposed to virulent M.tb in a ‘challenge’ experiment following vacci...

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Detalles Bibliográficos
Autores principales:	Tanner, Rachel, Hoogkamer, Emily, Bitencourt, Julia, White, Andrew, Boot, Charelle, Sombroek, Claudia C., Harris, Stephanie A., O'Shea, Matthew K., Wright, Daniel, Wittenberg, Rachel, Sarfas, Charlotte, Satti, Iman, Verreck, Frank A.W., Sharpe, Sally A., Fletcher, Helen A., McShane, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	F1000 Research Limited 2021
Materias:	Method Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097740/ https://www.ncbi.nlm.nih.gov/pubmed/33976866 http://dx.doi.org/10.12688/f1000research.51640.2

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